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Variety is Not the Spice of Life: Inconsistent Definitions of Failure After Hip Reconstruction in Cerebral Palsy
Eden N VanderHoek1, Yash Tarkunde1, Jeremy P Bauer2
1Department of Orthopaedics and Rehabilitation, Oregon Health and Science University.
Insights
Hip displacement is common in children with cerebral palsy (CP). A review found failure rates after hip reconstruction vary widely (1.8%–74%) due to inconsistent definitions, hindering outcome comparisons.
Area of Science:
- Orthopedic surgery
- Pediatric orthopedics
- Cerebral palsy research
Background:
- Hip displacement (subluxation/dislocation) is prevalent in children with cerebral palsy (CP), particularly nonambulatory individuals.
- Untreated hip displacement can lead to pain, stiffness, hygiene issues, and seating imbalance.
- Progressive displacement often necessitates surgery, with subsequent displacement termed 'failure,' lacking a standardized definition.
Purpose of the Study:
- To identify and compile published definitions of failure after index bony hip reconstruction in children with CP.
- To determine the reported failure rates associated with these diverse definitions.
Main Methods:
- A systematic review adhering to PRISMA guidelines was conducted using PubMed, SCOPUS, and OVID (1990-2023).
- Studies were included if they reported on bony hip reconstruction in CP, defined 'failure,' and excluded specific procedures (e.g., soft tissue-only, salvage, arthroplasty).
- Data extraction and bias assessment were performed by two authors, with a third resolving disagreements.
Main Results:
- Twenty-seven studies were included, revealing significant heterogeneity in failure definitions and reported rates (1.8% to 74%, mean 26.3%).
- Common failure definitions included Reimer Migration Percentage (MP) (63%) and revision surgery (48%).
- Heterogeneity, varied inclusion criteria, follow-up durations, and overlapping patient cohorts prevented meta-analysis.
Conclusions:
- A lack of a consistent definition for failure after bony hip reconstruction in CP complicates the comparison of surgical techniques and outcomes.
- Revision surgeries carry significant implications for medically complex children with CP.
- A standardized definition of failure is crucial for improving reporting and understanding of hip reconstruction outcomes in this population.
Background:
Hip displacement (subluxation or dislocation) is common in children with cerebral palsy (CP), especially those who are nonambulatory. If unaddressed, this can cause pain, stiffness, hygiene difficulties, and seating imbalance. Progressive hip subluxation or dislocation often requires surgery, and further displacement after reconstruction may be described as "failure." There is currently no standardized definition of failure after the index procedure. This review aimed to identify published failure definitions and compile reported failure rates after index bony hip reconstruction.
Materials And Methods:
Following PRISMA guidelines, a systematic review was performed using PubMed, SCOPUS, and OVID databases (1990 to 2023). Exclusion criteria included soft tissue-only procedures, gait analysis-based outcomes, adults, non-CP syndromes, salvage or arthroplasty procedures, nonoperative management, unavailable full-text, non-English articles, novel techniques, radiographic or morphologic studies, or procedures without osteotomy. Studies without a definition of "failure" were excluded. Abstract review, full-text screening, and data extraction were performed by 2 authors, with a third adjudicating disagreements. Patient demographics, failure definitions and rates, and study quality were collected. Bias was assessed, and data were considered for pooled analysis.
Results:
Of 630 abstracts, 27 studies were included. Failure rates ranged from 1.8% to 74% (mean 26.3%±17.4%). Definitions varied: Reimer Migration Percentage (MP) (63%) and revision surgery (48%) were most common. Other definitions included arthritis/hip pain (18.5%) and lateral center edge angle (18.5%). Significant heterogeneity in definitions, inclusion criteria, and follow-up, plus overlapping patient cohorts, precluded meta-analysis. The lowest rate (1.8%) reflected a single revision for painful instability. The highest (74%) came from a study defining failure as reoperation without MP. Two institutions contributed 6 publications.
Conclusions:
There is no consistent definition of failure after bony hip reconstruction in CP, impeding comparison of techniques and outcomes. Children with CP are medically complex, and revision surgeries have significant implications. We advocate for a more uniform definition of failure following hip reconstruction in children with CP.
Level Of Evidence:
Level III-systematic review of studies.
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