Assessment of genetically modified soybean MON 94313 (application GMFF-2022-6595).

Area of Science:

• Agricultural Science
• Biotechnology
• Food Safety

Background:

• Development of genetically modified (GM) soybean MON 94313 to enhance herbicide tolerance.
• Introduction of specific gene cassettes (dmo, pat, ft_t.1, tdo) for desired traits.

Purpose of the Study:

• To assess the food, feed, and environmental safety of GM soybean MON 94313.
• Evaluate potential risks associated with genetic modification and protein expression.

Main Methods:

• Molecular characterization and bioinformatics analysis.
• Agronomic, phenotypic, and compositional analysis compared to conventional soybean.
• Toxicity and allergenicity assessment of introduced proteins (DMO, PAT, FT_T.1, TDO).

Main Results:

• No safety concerns identified from molecular and bioinformatics data.
• Minor compositional differences (methionine, Gly m Bd 28K) evaluated and found safe.
• Introduced proteins (DMO, PAT, FT_T.1, TDO) deemed non-toxic and non-allergenic.
• No change in overall safety of soybean MON 94313 due to genetic modification.

Conclusions:

• Soybean MON 94313 is as safe as conventional counterparts for human and animal consumption.
• No nutritional concerns or environmental risks identified.
• Post-market monitoring for food/feed and environment not deemed necessary.