Related Experiment Video
Updated: Jan 24, 2026
Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Tinnitus, Dizziness and Hearing Status During Hypertension Diagnosis and Treatment
Hüseyin Kandemir1, Süheyla Kandemir2, Selçuk Öztürk1
1Department of Cardiology, Kırıkkale University Faculty of Medicine, Turkey.
Objective:
High blood pressure (BP) or hypertension (HTN) can impair hearing, causes tinnitus and dizziness. We hypothesized that there is an association between increased BP and hearing impairment (HI), tinnitus and dizziness, and decrease in BP improves these parameters and symptoms.
Methods:
The study included 100 newly-diagnosed HTN patients (systolic BP (SBP) ≥140 mmHg and/or diastolic BP (DBP) ≥90 mmHg) and 100 patients without HTN. Tinnitus and dizziness were evaluated through Tinnitus Handicap Inventory (THI) and Dizziness Handicap Inventory (DHI). The auditory status of all patients was assessed for both right ear (RE) and left ear (LE). BP measurements, THI, DHI, and audiometry tests were repeated at follow-up visit during treatment in HTN patients and delta (Δ) values were obtained.
Results:
The median of THI and DHI score and thresholds for hearing parameters were higher in HTN group. At follow-up visit, SBP, DBP, THI, DHI, and most of the hearing parameters significantly improved. ΔSBP significantly correlated with ΔRE average (logarithmically transformed (log10)) and ΔLE average (log10) in partial correlation analysis adjusted for age and Brinkman index. Multivariate linear regression analysis yielded an independent association of ΔRE average (log10) (Beta Coefficient (BC): 12.07, 95% Confidence Interval (CI): 1.86-22.29, P = .021) and ΔLE average (log10) (BC: 14.89, 95% CI: 5.45-24.33, P = .003) with ΔSBP. However, none of the parameters demonstrated an independent association with ΔDBP.
Conclusion:
HTN patients suffer from tinnitus, dizziness and HI, and BP decrease is associated with improvements in these symptoms and hearing status. Decrease in SBP rather than DBP is associated with improvements in hearing status.
Related Concept Videos
01:31Hearing
01:28Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
01:18Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme...
01:23Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
01:16Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
01:26Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...