Related Experiment Video
Updated: Jan 24, 2026

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
[A prolonged diagnostic examination of anal fissure with complicating contact dermatitis]
Camilla Møller1, Sebastian Vigand Svendsen1, Evy Paulsen1
1Hudafdeling og Allergicentret, Odense Universitetshospital.
Abstract:
The topical calcium channel blocker diltiazem gel is among the most frequently used medical treatments for anal fissures. A known side effect of diltiazem gel is contact dermatitis. This case report presents a 44-year-old woman, who was assessed by several different specialities, due to persistent perianal symptoms, while treated intermittently with diltiazem gel for an anal fissure. After 18 months, the patient was diagnosed with complicating allergic contact dermatitis caused by diltiazem gel.
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