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The In ovo CAM-assay as a Xenograft Model for Sarcoma
Published on: July 17, 2013
[Surgical management of bone sarcomas]
Sylvain Briand1, Charles Court1, Charlie Bouthors1
1Service de chirurgie orthopédique, AP-HP, GH université Paris-Saclay, DMU de chirurgie traumatologie orthopédique-chirurgie plastiquereconstruction, hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Abstract:
SURGICAL MANAGEMENT OF BONE SARCOMAS. Bone sarcoma surgery must be carried out by a specialized team, often multidisciplinary, integrated into the NetSarc+ network. Its main objective is to obtain appropriate margins to limit the risk of recurrence. Technical advances made in the resection and reconstruction of bone sarcomas have improved the quality of life of patients and reduced the amputation rate. Complications (infection, failure of reconstruction) are numerous, and surgical revisions are frequent. Functional after-effects (neurological deficits, chronic pain) are omnipresent and responsible for a disability that is sometimes difficult for the patient to accept. Collaboration between the surgical oncologist and the attending physician is an essential tool during the long-term follow-up of these patients.
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