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Central compartment atopic disease: Advances in pathogenesis and stratified treatment
Shaokun Huang1,2, Xuan Shan3, Chaofan Li1,2
1Qinghai University Clinical Teaching Hospital, Qinghai University, China.
Abstract:
Central compartment atopic disease is a recently delineated inflammatory endotype of chronic rhinosinusitis. It is characterized by involvement of the central intranasal compartment-the middle turbinate, superior turbinate, and posterior superior nasal septum-and is associated with a predominantly polypoid phenotype. This review synthesizes current evidence on local allergic pathophysiology, diagnostic frameworks, and stratified management of central compartment atopic disease to facilitate accurate diagnosis and individualized treatment.
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