Related Experiment Video
Updated: Jan 24, 2026

Author Spotlight: Advancing Syphilis Research — Innovations in Treponema pallidum Cultivation and Genetic Engineering
Published on: January 24, 2025
Peer-led community HIV/syphilis testing with linkage within seven days for MSM and transgender women in Indonesia: a
Sudirman1, Nittaya Phanuphak2, Siti Nadia Tarmizi3
1School of Global Health, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Abstract:
We evaluated a peer-led, community-based service (CBS) model providing integrated HIV/syphilis testing and referral for men who have sex with men (MSM) and transgender women (TGW) in South Sulawesi, Indonesia. Trained community health workers (CHWs) delivered finger-prick HIV RDTs and, where available, dual HIV/syphilis tests through three outreach modalities: door-to-door outreach, "static community posts", and mobile hotspot events. Primary outcomes were acceptability, feasibility , first-time testing, syphilis testing coverage, and linkage to confirmatory testing and ART within ≤7 days. Among 423 clients, acceptability was high, and most were first-time testers. HIV reactivity was 2.8% (12/423); all were referred, confirmed, and initiated ART within ≤7 days. Syphilis testing coverage was 83.0% with lower coverage in Bulukumba reflecting documented commodity/workflow constraints. In 70 observed encounters, checklist items 1-8 demonstrated complete procedural adherence; item 9 highlighted a need for documentation/SOP clarification for corrective actions when deviations occur. Qualitative findings converged with quantitative results: participants valued privacy, convenience, and peer trust, while stakeholders emphasized the need to stabilize test-kit supply, clarify corrective-action procedures, and strengthen client-level time-stamping for scale-up. Findings support scaling up differentiated, peer-led community testing for MSM and TGW with standardized quality assurance, and reliable syphilis test supply.
Related Concept Videos
Phosphodiester Linkages
Phosphodiester bond forms when a phosphoric acid molecule (H3PO4) links with two hydroxyl groups (–OH) of two other molecules, forming two ester bonds. Two water molecules are released in this process. The phosphodiester bond is commonly found in nucleic acids (DNA and RNA) and plays a critical role in their structure and function.
Phosphodiester Bonds Link Nucleotides Together
DNA and RNA are polynucleotides or long chains of nucleotides that are linked together. A nucleotide is...
Ligand Binding and Linkage
Ligand Binding and Linkage
What are Populations and Communities?
Influence of Parents and Peers on Identity
Parental Influence on Identity Development
Parents serve as primary guides and managers in an adolescent's life, offering support instrumental in decision-making and personal growth....
The Scientific Method in Nursing Process
When using research findings to change practice, one must understand the process used to guide a study. The scientific method is a systematic, step-by-step process that supports the data's validity, reliability, and generalizability. As a result, findings can be...

