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Updated: Jan 25, 2026

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
Published on: May 21, 2013
Osteochondral Allograft Reconstruction for Post-traumatic Osteo-Articular Defects of the Knee: A Case Report
Siva Srivastava Garika1, Nitish Jagdish Jyoti1, Vijay Sharma1
1Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India.
Case:
A 21-year-old male sustained a high-velocity open knee injury with extensive osteochondral loss of the lateral femoral condyle, patella, and proximal tibia with an intact extensor apparatus. Following staged debridement and external stabilization, reconstruction was performed using a size-matched osteochondral allograft (OCA). The graft was contoured to restore condylar geometry and incorporated using internal fixation. At the 2-year follow-up, radiographs confirmed graft incorporation and the patient demonstrated excellent functional recovery.
Conclusion:
OCA transplantation is a valuable joint-preserving option for massive post-traumatic defects in young patients. In open injuries, careful planning, staged reconstruction, and size-matched graft-selection are critical for successful outcomes.
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