Feasibility and safety of double-J ureteral stent with a timed-release extraction string in children
1Department of Pediatric Surgery, Women and Children's Hospital of Ningbo University, Ningbo 315012, China.
Insights
The double-J ureteral stent with a timed-release extraction string (DJUS-TRES) offers a safe, anesthesia-free option for pediatric stent removal. While most removals were successful, potential complications like UTIs and urinary symptoms require consideration.
Area of Science:
- Pediatric Urology
- Minimally Invasive Surgery
- Medical Device Innovation
Background:
- Conventional double-J ureteral stent (DJUS) removal in children necessitates cystoscopy under general anesthesia, posing risks and increasing costs.
- The development of DJUS with a timed-release extraction string (DJUS-TRES) aims to mitigate these limitations.
Purpose of the Study:
- To assess the feasibility and safety of utilizing DJUS-TRES for stent removal in pediatric patients.
- To compare the outcomes of DJUS-TRES removal with traditional cystoscopic methods.
Main Methods:
- A prospective data collection of pediatric patients undergoing urological surgery with DJUS-TRES placement, followed by retrospective analysis.
- Postoperative assessment of spontaneous string expulsion and subsequent stent removal via traction, with cystoscopic removal reserved for failures.
Main Results:
- Successful DJUS-TRES placement was achieved in 94.5% of pediatric patients (n=69/73).
- Stent removal via traction was successful in 90.9% (n=60/66) of attempted cases within two months.
- Complications included stent-associated urinary tract infection (18.8%), urinary symptoms (13.0%), stent migration (5.8%), and severe encrustation (1.5%).
Conclusions:
- DJUS-TRES facilitates anesthesia-free stent removal in most pediatric cases, offering a favorable safety profile and reduced tissue trauma.
- Antegrade placement failures (14%) were primarily linked to ureterovesical junction passage issues.
- Despite a moderately lower success rate compared to invasive methods, DJUS-TRES presents a viable alternative, though further controlled studies are warranted.
Introduction:
Conventional removal of double-J ureteral stent (DJUS) in children typically requires cystoscopy under general anesthesia, which entails perioperative risks and increased healthcare costs. The DJUS with a timed-release extraction string (DJUS-TRES) potentially overcomes these limitations.
Objective:
To evaluate the feasibility and safety of DJUS-TRES in children.
Study Design:
We prospectively collected data on children undergoing urological surgeries with DJUS-TRES between September 2022 and May 2025, with subsequent retrospective analysis. Postoperatively, the absorbable suture securing the extraction string undergoes hydrolysis, releasing the string. Once the string is spontaneously expelled through the urethra, the stent can be removed by traction in an outpatient settings or at home. Cystoscopic removal was reserved for cases where the string was not expelled after two months or if traction removal was unsuccessful.
Results:
DJUS-TRES was successfully placed in 69 out of 73 children (94.5 %), with a median age of 3.6 years (range: 1.2 months to 16 years). All four placement failures occurred during antegrade approach, due to inability to pass the ureterovesical junction (UVJ) (n = 2), misplacement into the preputial cavity (n = 1), and ureteral retention of the extraction string (n = 1). String removal was attempted within two months in 66 cases and was successful in 60 (90.9 %). Causes of failure included non-expulsion due to encrustation (n = 4) and string fracture during traction (n = 2). Complications included one case (1.5 %) of severe encrustation requiring pneumovesicoscopic removal, stent migration (n = 4, 5.8 %), stent-associated urinary tract infection (UTI; n = 13, 18.8 %), and significant urinary symptoms (n = 9, 13.0 %).
Discussion:
DJUS-TRES enabled stent removal without anesthesia or invasive procedures in most patients. However, several specific characteristics were observed. First, antegrade placement failed in approximately 14 % of attempts, primarily due to impaired passage of the distal stent end across the UVJ. Second, it carries a risk of urinary symptoms-such as foreign body sensation, urinary incontinence, and dysuria-likely resulting from the string in the urethra, interfering with sphincter function and causing obstructive voiding. Third, the most common complication was UTI, with stent migration and string encrustation occurring less frequently. Although the success rate of DJUS-TRES removal was moderately lower, it offered a favorable safety profile and minimized tissue damage compared to cystoscopy and other invasive alternatives.
Conclusion:
The DJUS-TRES provides a safe and effective option for stent removal without the need for cystoscopy or anesthesia. Given the risks of failure and complications, further prospective controlled studies are warranted to evaluate its clinical efficacy.
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