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Updated: Jan 25, 2026

Protein Purification-free Method of Binding Affinity Determination by Microscale Thermophoresis
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Robust SH2 binding affinity indicates minimal SH3-to-SH2 communication in Grb2

Eduarda Santos Ventura1,2, Mariana Di Felice1,2, Julian Toso1,2

  • 1Dipartimento di Scienze Biochimiche "A. Rossi Fanelli", Sapienza Università di Roma, Rome, 00185, Italy.

Biology Direct
|January 24, 2026
PubMed
Summary

No abstract available in PubMed .

Keywords:
Adaptor proteinsAllosteryKineticsSite-directed mutagenesis

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