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Updated: Jan 26, 2026

siRNA Screening to Identify Ubiquitin and Ubiquitin-like System Regulators of Biological Pathways in Cultured Mammalian Cells
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Reversible ubiquitination regulates HSF1 phase separation in response to proteotoxic stress

Yue Zhu1, Jianhua Wang2, Shuhong Tang2

  • 1The Fifth People's Hospital of Dalian, Dalian Medical University, Dalian, China; Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China.

Life Sciences
|January 24, 2026
PubMed
Abstract

Keywords:
Deubiquitinating enzymeE3 ligaseHSF1Phase separationProteotoxic stressUbiquitination

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