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Actinomucor elegans in Human Infections: A Case Report and Narrative Review of the Literature

Andrea Cosentino1,2, Daniel Vescoli3, Wilhelm Berger4

  • 1Department of Orthopedics and Traumatology, Hospital of Merano (SABES-ASDAA), Teaching Hospital of the Paracelsus Medical University, Merano-Meran, Italy. andreacosentino2@gmail.com.

Mycopathologia
|January 25, 2026
PubMed
Abstract

Insights

Actinomucor elegans causes invasive mucormycosis in immunocompromised and trauma patients. Early diagnosis and antifungal treatment are crucial for survival in these rare infections.

Area of Science:

  • Medical Mycology
  • Infectious Diseases

Background:

  • Actinomucor elegans is an underrecognized cause of invasive mucormycosis.
  • Infections occur in immunocompromised individuals and trauma patients.

Purpose of the Study:

  • To present a case of cutaneous A. elegans infection.
  • To review literature on A. elegans clinical presentation, diagnostics, and outcomes.

Main Methods:

  • Case report and narrative literature review.
  • Searched PubMed and Embase for human A. elegans cases.
  • Extracted data on demographics, comorbidities, infection site, diagnostics, treatments, and outcomes.

Main Results:

  • Six cases identified: immunocompromised and trauma patients.
  • Infection sites included pulmonary, rhino-orbital, cutaneous, and disseminated forms.
  • Mortality rate was 50%; survival linked to early diagnosis and antifungal therapy.

Conclusions:

  • Actinomucor elegans causes severe infections in high-risk patients.
  • Early recognition and microbiological diagnostics are critical.
  • Aggressive antifungal management improves patient outcomes.
Keywords:
Actinomucor elegansImmunosuppressionInvasive fungal infectionLiposomal amphotericin BMucormycosisReviewTrauma

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