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Updated: Jan 28, 2026
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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
12.5K
Preexisting Heart Disease Spectrum and In-Hospital Outcomes for Patients With Acute Ischemic Stroke
Hong-Qiu Gu1,2, Kai-Xuan Yang1,2, Xing-Quan Zhao3
1China National Clinical Research Center for Neurological Diseases Beijing Tiantan Hospital Capital Medical University Beijing China.
Stroke (Hoboken, N.J.)
|January 26, 2026
Summary
Preexisting heart conditions, especially atrial fibrillation, worsen stroke outcomes. Patients with these conditions face higher risks of severe stroke, in-hospital death, and reduced mobility.
Area of Science:
- Cardiology
- Neurology
- Public Health
Background:
- Individual heart conditions' impact on stroke is known.
- Combined effects of heart conditions on stroke outcomes are understudied.
Purpose of the Study:
- To investigate the association between combined preexisting heart diseases and in-hospital stroke outcomes.
Main Methods:
- Analysis of acute ischemic stroke patient data from the Third China National Stroke Registry.
- Definition of preexisting heart disease spectrum based on combinations of coronary heart disease, atrial fibrillation, and heart failure.
- Assessment of in-hospital stroke outcomes including stroke severity, ambulation, and mortality.
Main Results:
- 13.2% of 14,019 patients had preexisting heart diseases.
- Patients with heart diseases had higher rates of severe stroke and in-hospital death, and lower ambulation rates.
- Atrial fibrillation, alone or combined with other heart diseases, showed the strongest association with adverse stroke outcomes.
Conclusions:
- Preexisting heart diseases are linked to unfavorable in-hospital stroke outcomes.
- Atrial fibrillation, particularly when combined with other heart conditions, significantly increases stroke severity, mortality, and disability.
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