Related Experiment Video

Updated: Jan 28, 2026

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

19.2K

Absent Left Main Coronary Artery with Separate Origin of Left Anterior Descending Artery and Left Circumflex Artery

Damandeep Singh1, Niraj Nirmal Pandey1, Neeraj Parakh2

  • 1Department of Cardiovascular Radiology & Endovascular Interventions, All India Institute of Medical Sciences, New Delhi-110029, India.

Methodist Debakey Cardiovascular Journal
|January 26, 2026
PubMed

Insights

A rare coronary artery anomaly, the absence of the left main coronary artery, was identified in a patient with chest pain. This congenital variation involves separate origins for major coronary arteries, impacting cardiac procedures.

Area of Science:

  • Cardiovascular medicine
  • Medical imaging
  • Anatomical variations

Background:

  • Atypical chest pain can stem from various cardiac conditions.
  • Congenital coronary artery anomalies are uncommon but clinically significant.
  • Accurate diagnosis of coronary anatomy is crucial for patient management.

Purpose of the Study:

  • To report a unique case of coronary artery anomaly.
  • To illustrate the diagnostic utility of coronary computed tomography angiography.
  • To discuss the implications of this anomaly in clinical practice.

Main Methods:

  • Case report of a 49-year-old female patient.
  • Utilized electrocardiogram-gated coronary computed tomography angiography for detailed cardiac imaging.
  • Analyzed the origin and course of the coronary arteries.

Main Results:

  • Identified the absence of the left main coronary artery segment.
  • Observed separate ostia for the left anterior descending artery and left circumflex artery originating directly from the left coronary sinus.
  • Confirmed a rare congenital coronary artery anomaly.

Conclusions:

  • The absence of the left main coronary artery is a rare anomaly.
  • Coronary computed tomography angiography is effective in diagnosing such variations.
  • This anatomical variation has significant procedural implications for cardiac interventions.

Keywords:
absent left main coronary arteryanomalous coronary artery origincoronary artery anomalycoronary computed tomography angiography

More Related Videos

Murine Myocardial Infarction Model using Permanent Ligation of Left Anterior Descending Coronary Artery08:38

Murine Myocardial Infarction Model using Permanent Ligation of Left Anterior Descending Coronary Artery

Published on: August 16, 2019

29.5K
Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure09:37

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure

Published on: December 2, 2014

28.7K

Related Concept Videos

Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.0K
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
415
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
246
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
359
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
658
Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
632