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Updated: Jan 28, 2026

Tissue-simulating Phantoms for Assessing Potential Near-infrared Fluorescence Imaging Applications in Breast Cancer Surgery
Published on: September 19, 2014
An accurate analytical modeling method for microwave-based breast tumor detection and phantom manufacturing
Kyrillos Youssef1,2, Ahmed H Abd El-Malek1, Haruichi Kanaya3
1Department of Electronics and Communications Engineering, Egypt-Japan University of Science and Technology, New Borg El-Arab City, Alexandria, Egypt.
Abstract:
Early detection of breast cancer significantly improves survival rates, with nearly all patients surviving for over five years. Mathematical modeling of cancerous tissue dynamics facilitates the rapid detection of tumors. This study introduces an innovative segmented hemispherical modeling approach for breast tissue, wherein the tissues are modeled as electrical capacitors with unequal plates. The structure and performance of the proposed hemispherical model are thoroughly examined. The effective permittivity, [Formula: see text], of both individual breast tissues and the entire breast is computed using their dielectric properties. The proposed closed-form breast model is analyzed and compared with state-of-the-art methods through analytical, simulation-based, and experimental approaches. The proposed segmented hemispherical modeling technique significantly outperforms traditional cubic models, achieving substantially higher discrimination levels of 0.335 compared to 0.001 for fatty breast tissue and 0.412 compared to 0.001 for dense breast tissue. The model accurately replicates real breast anatomy and demonstrates superior efficacy in tumor detection, showing a simulated difference of 3 dB and 7 degrees in the magnitude and phase of the [Formula: see text]-parameters, respectively. Furthermore, the proposed method holds promising potential for developing an affordable and simple breast phantom fabrication method that, if adopted, could significantly facilitate research in laboratory settings. These phantoms would maintain high accuracy in replicating real breast tissue and contribute to more practical and reliable results in breast cancer detection techniques.
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