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Unveiling the hidden: acquired pediatric hypothyroidism.
Mariacarolina Salerno1,2, Donatella Capalbo1,3, Mariella Valenzise4
1Department of Translational Medical Sciences, Pediatric Endocrinology Unit, University of Naples Federico II, Naples, Italy.
Acquired hypothyroidism in children, often caused by Hashimoto thyroiditis, presents diverse symptoms. Early diagnosis and management are crucial for optimal growth and development in pediatric patients.
Area of Science:
- Pediatric Endocrinology
- Internal Medicine
- Clinical Case Review
Background:
- Acquired hypothyroidism is the most common thyroid disorder in children.
- Hashimoto thyroiditis is the primary cause in iodine-sufficient areas.
- Clinical presentations vary, complicating diagnosis and potentially impacting development.
Purpose of the Study:
- To summarize current knowledge on acquired hypothyroidism in children.
- To illustrate typical and atypical manifestations through real-life pediatric cases.
- To aid pediatricians in identifying and managing pediatric hypothyroidism.
Main Methods:
- Review of four pediatric cases with acquired hypothyroidism.
- Comprehensive overview of etiology, clinical presentation, diagnosis, and management.
- Literature synthesis on pediatric acquired hypothyroidism.
Main Results:
- Cases presented typical and atypical signs of acquired hypothyroidism.
- Varied presentations underscore diagnostic challenges.
- Timely intervention is critical for pediatric outcomes.
Conclusions:
- Acquired hypothyroidism requires vigilant diagnosis in children.
- Understanding diverse presentations aids pediatricians.
- Effective management is key to preventing adverse growth and developmental effects.
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