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Updated: Jan 28, 2026

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
Published on: September 17, 2014
A Practical Approach to Corneal Perforation in the Absence of Donor Tissue
Swaranjali Gore1, Himani Yadav, Lokisha Chandwani
1Department of Ophthalmology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India.
This case report details an emergency technique using a sterile polydrape patch and cyanoacrylate glue to seal traumatic corneal perforations. This low-cost method offers a viable solution when donor corneal tissue is unavailable, especially in resource-limited settings.
Area of Science:
- Ophthalmology
- Trauma Surgery
- Emergency Medicine
Background:
- Traumatic corneal perforations pose a significant risk to vision.
- Access to donor corneal tissue for grafting can be limited in emergency and resource-limited settings.
Purpose of the Study:
- To present an emergency surgical technique for managing traumatic sealed corneal perforations.
- To demonstrate a low-cost, accessible method for restoring globe integrity when donor tissue is unavailable.
Main Methods:
- A sterile surgical polydrape patch was used to cover a 4 mm x 3 mm corneal perforation.
- N-butyl-cyanoacrylate glue secured the patch, followed by a bandage contact lens.
- The procedure was performed in an emergency setting due to lack of donor corneal graft material.
Main Results:
- The globe-sealing procedure successfully restored ocular integrity.
- The patient experienced an uneventful recovery with a healed cornea and maintained anterior chamber at 1-month follow-up.
- No signs of infection or persistent inflammation were observed.
Conclusions:
- A sterile polydrape patch combined with cyanoacrylate adhesive is an effective and accessible emergency solution for traumatic corneal perforations.
- This technique provides a critical interim measure for globe stabilization, facilitating healing or referral in under-resourced environments.
- It offers a valuable, low-cost alternative to donor corneal grafts in urgent situations.
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