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Personalized Nanocomposite-based Drug Delivery Systems: Integration of AI and 3D Printing
Chintan Aundhia1, Ghanshyam Parmar1, Chitrali Talele1
1Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Waghodia, Vadodara, 391760, Gujarat, India.
Current Drug Targets
|January 26, 2026
Summary
Artificial intelligence (AI) and 3D printing are revolutionizing personalized drug delivery using polymeric nanocomposites. These technologies enhance precision, efficacy, and customization for improved patient outcomes.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Pharmaceutical Sciences
Background:
- Emerging role of AI and 3D printing in personalized medicine.
- Focus on polymeric nanocomposite-based drug delivery systems.
- Enhancing precision, efficacy, and customization of pharmacotherapy.
Purpose of the Study:
- Comprehensively discuss AI and 3D printing in personalized drug delivery.
- Elucidate design principles, fabrication methods, and synergistic applications.
- Highlight advancements over conventional formulations.
Main Methods:
- Extensive literature survey of PubMed, Scopus, Web of Science, ScienceDirect (past decade).
- Critical analysis of peer-reviewed studies, reviews, and reports.
- Synthesis of data on AI, 3D printing, and polymeric nanocomposites.
Main Results:
- Polymeric nanocomposites offer superior targeted and controlled drug release.
- AI enables predictive modeling and formulation optimization.
- 3D printing allows patient-specific dosage forms with programmable release.
Conclusions:
- Synergistic AI and 3D printing integration overcomes formulation challenges in precision medicine.
- Enables individualized therapeutic systems for better treatment outcomes.
- Promising applications in cancer, diabetes, neurodegenerative, infectious, and cardiovascular diseases.
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