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Lyme Carditis Identified by a Novel Syndromic Surveillance Definition, New York State, 2017-2021
Amy M Beeson1,2, Jennifer L White3, Abigail L Gates4
1Bacterial Diseases Branch, Division of Vector-borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA.
Public Health Reports (Washington, D.C. : 1974)
|January 27, 2026
Summary
A new definition helps identify Lyme carditis cases in New York State. This tool can track changes in Lyme disease manifestations, aiding public health surveillance.
Area of Science:
- Public Health
- Infectious Disease Epidemiology
- Syndromic Surveillance
Background:
- Lyme carditis is a severe manifestation of Lyme disease.
- Systematic data collection on Lyme carditis clinical features is lacking in the US.
- A syndromic surveillance definition was needed to monitor Lyme carditis.
Purpose of the Study:
- To develop and validate a syndromic surveillance definition for identifying Lyme carditis cases.
- To characterize Lyme carditis cases in New York State (NYS) from 2017-2021.
Main Methods:
- Utilized the National Syndromic Surveillance Program's BioSense Platform with diagnostic codes and keywords.
- Reviewed medical records from NYS's regional health information exchange for case abstraction.
- Physician reviewers independently confirmed case status and mapped geographic distribution.
Main Results:
- Identified 82 confirmed or probable Lyme carditis cases out of 173 initial records (47% positive predictive value).
- Cases occurred in 49% of NYS counties, peaking in July and August.
- Affected individuals had a bimodal age distribution (peaks at ~32 and ~70 years), predominantly males (71%), with high rates of positive serology (84%) and AV block (67%).
Conclusions:
- The developed definition is a valuable tool for detecting shifts in Lyme carditis patterns.
- Effective for surveillance in regions with high Lyme disease incidence.
- Highlights the utility of syndromic surveillance for monitoring specific disease manifestations.
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