Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biodiversity and Human Values01:24

Biodiversity and Human Values

17.0K
Human civilization relies on biodiversity in many ways. Sudden changes in species biodiversity result in environmental changes that can modify weather patterns and therefore human civilizations.
17.0K
Regulated mRNA Transport02:22

Regulated mRNA Transport

7.0K
In eukaryotes, transcription and translation are compartmentalized; an mRNA is first synthesized in the nucleus and then selectively transported to the cytoplasm for protein synthesis. Before transport, a pre-mRNA undergoes several steps of post-transcriptional modifications including splicing, 5' capping, and the addition of a poly-adenine tail. Various proteins bind to the pre-mRNA during these modifications. The mRNA transport takes place with the help of multiple proteins playing...
7.0K
Human Genetics01:28

Human Genetics

1.6K
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
1.6K
Requirements for Human Life01:26

Requirements for Human Life

13.5K
The Earth and its atmosphere have provided humans with air, water, and food, but these are not the only requirements for survival. Humans also require a specific range of temperature and pressure that the Earth and its atmosphere provides.
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
13.5K
Role of Proteins in the Human Body01:28

Role of Proteins in the Human Body

6.4K
Proteins are the building block of life. They are also  the most abundant macromolecules with as many diverse roles in the body. They are part of many structural components that provide unique shapes and structures to animal cells, tissues, and organs. In addition, they also act as biological catalysts and carry out several anabolic and catabolic reactions. Notably, some proteins are chemical messengers and regulate many critical processes, such as metabolism, growth, and development. They...
6.4K
Maslow's Theory of Basic Human Needs01:28

Maslow's Theory of Basic Human Needs

3.2K
Maslow's hierarchy is described with the help of a pyramidal shape. The most fundamental needs, physiological needs, are at the bottom of the pyramid.
Physiological needs such as hunger, thirst, sex, physical comfort, and survival are at the bottom of the pyramid. These are the components that are necessary to sustain life. Once the first level of needs has been met, the second level arises.
Safety needs include stability and predictability. Protection and freedom from danger are all a part...
3.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Successful Scale-up of Syphilis Testing Linked to Routine HIV Viral Load Monitoring in British Columbia.

Open forum infectious diseases·2026
Same author

The lenacapavir paradox: why a promising prevention tool raises difficult questions about African HIV response priorities.

The Lancet. Global health·2026
Same author

Changes in Clinician Time Expenditure and Visit Quantity With Adoption of Artificial Intelligence-Powered Scribes: A Multisite Study.

JAMA·2026
Same author

Efficacy of Minocycline in Acute Traumatic Spinal Cord Injury.

Journal of neurotrauma·2026
Same author

The 31st Lilian Lindsay Memorial Lecture.

British dental journal·2026
Same author

Incidence of Herpes Zoster Infection (Shingles) Among Adults Living With and Without HIV in British Columbia, Canada: A Population-Based Study.

The Journal of infectious diseases·2026

Related Experiment Video

Updated: Jan 29, 2026

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
11:10

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3

Published on: December 27, 2010

12.7K

Inaction against HIV/AIDS remains a crime against humanity.

Julio S G Montaner1,2, Reuben Granich3, Brian Williams4

  • 1BC Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada jmontaner@bccfe.ca.

Sexually Transmitted Infections
|January 27, 2026
PubMed
Summary

Reducing funding for the President's Emergency Plan for AIDS Relief (PEPFAR) risks millions of new HIV infections and deaths. Continued investment is crucial for global HIV prevention and treatment efforts.

Keywords:
AIDSHIVPUBLIC HEALTH

More Related Videos

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
08:15

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Published on: January 31, 2020

9.1K
Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
09:54

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models

Published on: December 3, 2019

10.6K

Related Experiment Videos

Last Updated: Jan 29, 2026

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
11:10

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3

Published on: December 27, 2010

12.7K
Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
08:15

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Published on: January 31, 2020

9.1K
Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
09:54

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models

Published on: December 3, 2019

10.6K

Area of Science:

  • Global Health
  • Infectious Diseases
  • Public Health Policy

Background:

  • Antiretroviral therapy (ART) is critical for preventing HIV illness, death, and transmission.
  • Pre-exposure prophylaxis (PrEP) offers a vital tool for HIV prevention in high-risk populations.
  • The President's Emergency Plan for AIDS Relief (PEPFAR) has been a cornerstone of global HIV/AIDS response since 2003.

Purpose of the Study:

  • To highlight the significant impact of PEPFAR on global HIV/AIDS outcomes.
  • To underscore the severe consequences of reduced funding for PEPFAR.
  • To advocate for sustained international commitment to HIV/AIDS initiatives.

Main Methods:

  • Analysis of PEPFAR's achievements over two decades.
  • Review of UNAIDS modeling on potential funding cuts.
  • Assessment of the impact of reduced overseas development funding on HIV services.

Main Results:

  • PEPFAR has provided ART to over 20 million people, saved over 25 million lives, and enabled millions of HIV-free births.
  • PEPFAR has contributed to halving new HIV infections in highly impacted countries.
  • Projected UNAIDS data indicates potential for 6 million additional HIV infections and 4 million AIDS deaths by 2029 if funding is permanently lost.

Conclusions:

  • Dismantling PEPFAR jeopardizes decades of progress in the global fight against HIV/AIDS.
  • Sustained funding for PEPFAR is essential to prevent a resurgence of HIV infections and AIDS-related deaths.
  • Urgent reflection by US administration and G7 leaders is needed to maintain global health security and address the HIV/AIDS epidemic.