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Respiratory capacities are crucial indicators of lung function, representing the maximum amount of air an individual's respiratory system can handle during various breathing phases.
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Movement joints in buildings are essential design elements that accommodate inevitable motions caused by various factors such as temperature changes, moisture content variations, and structural deflections. These motions, if not considered in design and construction, can lead to unsightly or dangerous damage. Movement joints are incorporated in different forms to manage these stresses and allow materials to move without causing distress.
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Building stones, essential materials for construction, are extracted from natural rock deposits and processed into specific forms and dimensions suitable for various building applications. These stones are broadly classified into three types based on their geological formation: igneous, sedimentary, and metamorphic.
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Buffers: Buffer Capacity01:09

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Buffer capacity is the quantitative measure of a buffer to resist the change in pH. As shown in the following equation, the buffer capacity, denoted by 'beta', is expressed as the number of moles of acid or base needed to change the pH of a one-liter buffer solution by 1 unit. Here, Ca and Cb indicate the number of moles of acid and base, respectively. Note that dpH represents the change in pH.
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The respiratory system is responsible for the intake of oxygen and the expulsion of carbon dioxide from the body. Respiratory volumes describe the volume of air in the lungs at different phases of the respiratory cycle. Tidal volume is the air breathed in and out during normal, quiet breathing. Inspiratory reserve volume is the air that can be forcefully inspired beyond the tidal volume. In contrast, expiratory reserve volume refers to the air that can be expelled from the lungs after a normal...
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Innovating HTA: a call for capacity building and standardization.

Diana M J Delnoij1,2, Dalia M Dawoud3, Jamie Elvidge4

  • 1https://ror.org/038b4c997National Health Care Institute, Netherlands.

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This summary is machine-generated.

Innovating health technology assessment (HTA) requires better data standardization and European collaboration to ensure equitable access to new health technologies. Capacity building is crucial, but resource limitations necessitate prioritization by HTA agencies.

Keywords:
European collaborationcapacity buildinghealth technology assessmentinnovationreal-world evidence

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Area of Science:

  • Health Technology Assessment (HTA)
  • Health Economics
  • Health Policy and Governance

Background:

  • New health technologies emerge amid resource scarcity, necessitating efficient Health Technology Assessment (HTA) to guide decision-making.
  • HTA supports equitable and affordable access to effective innovations, a critical challenge in healthcare systems.
  • The Horizon2020 project focused on innovating HTA methods to address these challenges.

Purpose of the Study:

  • To summarize policy-related findings from a Horizon2020 project on innovative HTA methods.
  • To discuss the implications of these findings for the governance of HTA in Europe.
  • To identify challenges and propose solutions for advancing HTA practices.

Main Methods:

  • Thematic analysis of 18 policy-oriented papers from the Next Generation Health Technology Assessment (HTx) project.
  • Online survey and a 2-day meeting involving 21 European and global stakeholders.
  • Stakeholder feedback collection on proposed solutions and prioritization of future strategies.

Main Results:

  • Key challenges identified include lack of standardized data access, varying evidentiary needs, and insufficient HTA capacity.
  • Proposed solutions encompass capacity building, national/international dialogues, standardization, and enhanced European collaboration.
  • Stakeholders exhibited diverse expectations regarding the success of the proposed solutions.

Conclusions:

  • Aligning evidentiary needs through dialogue, standardization via European collaboration, and capacity building are essential for HTA innovation.
  • Without increased investment in personnel, HTA agencies face prioritization dilemmas.
  • While European collaboration is vital, global alignment may be necessary for effective standardization.