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Updated: Jan 29, 2026

A Quantitative Fitness Analysis Workflow
Published on: August 13, 2012
Fitness in CLL
Claudia Baratè1, Ilaria Scortechini2, Sara Ciofini3
1Department of Hematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, 20161 Milano, Italy.
Abstract:
The increased complexity of CLL management, driven by the advent of targeted therapies, makes it necessary to redefine the concept of fitness, which until a few years ago was limited to the patient's ability to undergo chemoimmunotherapy. In the current therapeutic landscape, fitness assessment must also consider biological age, comorbidities, and frailty, which have become increasingly relevant due to evolving treatment options and a more nuanced understanding of the elderly CLL population. In this context, the general condition of the patient should be preserved with greater attention to physical activity and nutrition. This narrative review analyzed in depth all these aspects with the aim of providing insights into fitness assessments and their actualization.
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