Related Experiment Video

Updated: Jan 29, 2026

Establishment of Viral Infection and Analysis of Host-Virus Interaction in Drosophila Melanogaster
09:57

Establishment of Viral Infection and Analysis of Host-Virus Interaction in Drosophila Melanogaster

Published on: March 14, 2019

11.3K

Respiratory Viral Infection Prophylaxis and Treatment in the Transplant Population

Adriana A M Giuliani1,2, Victor Chen3, Nancy Law1

  • 1Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California, La Jolla, CA 92093, USA.

Viruses
|January 28, 2026
PubMed

Insights

Transplant patients face risks from respiratory viral infections (RVIs). New vaccines and treatments offer hope, but their safety and effectiveness in transplant recipients require further study to improve outcomes.

Area of Science:

  • Immunology
  • Virology
  • Transplant Medicine

Background:

  • Respiratory viral infections (RVIs) are a significant cause of morbidity and mortality in transplant patients.
  • Recent advancements in understanding virus structure have led to the development of new prophylactic and therapeutic agents, including vaccines.

Purpose of the Study:

  • To review the current landscape of RVIs in transplant populations.
  • To discuss the efficacy, safety, and timing of vaccines, antivirals, and other novel agents for RVI prevention and treatment in transplant recipients.

Main Methods:

  • Literature review of current RVI prophylaxis and treatment strategies.
  • Analysis of data on vaccine timing, safety, and efficacy.
  • Examination of novel agents, including antivirals and monoclonal antibodies.

Main Results:

  • New vaccines, antivirals, and monoclonal antibodies are emerging for RVIs.
  • The utility and safety of these agents in transplant populations are often uncertain.
  • Specific focus on influenza, SARS-CoV-2, and RSV in the context of transplantation.

Conclusions:

  • Despite knowledge gaps, advancements in RVI prevention and treatment hold promise for improving outcomes in transplant patients.
  • Further research is needed to establish optimal use of new agents in this vulnerable population.
Keywords:
RSVSARS-CoV-2antiviralinfluenzamonoclonal antibodyvaccination

More Related Videos

Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant08:52

Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant

Published on: May 27, 2011

17.7K
Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections16:56

Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections

Published on: August 30, 2014

17.6K

Related Concept Videos

Viral Recombination00:57

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
25.1K
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
612
Conservation of Small Populations02:04

Conservation of Small Populations

Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
17.1K
What is Population Genetics?01:25

What is Population Genetics?

A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
64.7K
Population Growth00:57

Population Growth

Population size is dynamic, increasing with birth rates and immigration, and decreasing with death rates and emigration. In ideal conditions with unlimited resources, populations can increase exponentially, which plots as a J-shaped growth rate curve of population size against time. This type of curve is characteristic of newly-introduced invasive species, or populations that have suffered catastrophic declines and are rebounding.
28.4K
Viral Structure00:56

Viral Structure

Viruses are extraordinarily diverse in shape and size, but they all have several structural features in common. All viruses have a core that contains a DNA- or RNA-based genome. The core is surrounded by a protective coat of proteins called the capsid. The capsid is composed of subunits called capsomeres. The capsid and genome-containing core are together known as the nucleocapsid.
74.4K