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Updated: Jan 30, 2026

A 3D System for Culturing Human Articular Chondrocytes in Synovial Fluid
Published on: January 31, 2012
Synovial Sarcoma with Extensive Rhabdoid Differentiation: A Rare Aggressive and Deceptive Histological Subtype
Sunil Pasricha1, Divya Bansal1, Himanshu Rohela1
1Department of Pathology, Rajiv Gandhi Cancer Institute & Research Centre, DELHI, INDIA.
Objective:
Synovial sarcoma usually presents with spindle cell morphology with or without epithelial differentiation. Extensive rhabdoid differentiation is a very rare feature with only few cases described in literature.
Case Report:
We present two cases of synovial sarcoma with rhabdoid differentiation along with their clinical follow-up. Both cases had tumor in the vicinity of joints and showed lung metastasis during follow-up inspite of R0 resection.
Conclusion:
We emphasised that extensive rhabdoid differentiation can be deceptive and challenging for diagnosis in small biopsies and also show an aggressive clinical course with dismal prognosis. Awareness of this rarely described unusual and aggressive histomorphological subtype is prudent due to its distinct diagnostic, prognostic and therapeutic implications.
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