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Updated: Jan 30, 2026

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Published on: July 5, 2011
Does Use of Technology Affect Manipulation Under Anesthesia Rates in Total Knee Arthroplasty?
Theodor Di Pauli von Treuheim1, Filippo Romanelli1, Muhammad Haider2
1Department of Orthopedics, NYU Langone Orthopedic Hospital, New York, New York, United States.
Computer-navigated and robotic-assisted total knee arthroplasty (TKA) do not increase manipulation under anesthesia (MUA) rates compared to conventional TKA. However, specific fixation methods and implant designs used with robotic-assisted TKA are associated with higher MUA risk.
Area of Science:
- Orthopedic Surgery
- Biomedical Engineering
- Arthroplasty Research
Background:
- Arthrofibrosis following total knee arthroplasty (TKA) can lead to patient dissatisfaction.
- Manipulation under anesthesia (MUA) is a procedure to improve range of motion post-TKA.
- Computer-navigated and robotic-assisted technologies aim to enhance TKA precision and potentially reduce MUA rates.
Purpose of the Study:
- To investigate the impact of computer-navigated (N-TKA) and robotic-assisted (R-TKA) total knee arthroplasty on manipulation under anesthesia (MUA) rates compared to conventional TKA (C-TKA).
- To identify specific surgical factors associated with MUA in navigated and robotic-assisted TKA procedures.
Main Methods:
- A retrospective review of 18,815 primary, elective, unilateral TKAs performed between 2010 and 2022.
- Patients were categorized into conventional (C-TKA), computer-navigated (N-TKA), and robotic-assisted (R-TKA) groups.
- MUA rates were analyzed using ANOVA and multivariate logistic regression, considering fixation modes and implant constraints.
Main Results:
- The overall MUA rate was 1.7%, with R-TKA showing a higher rate (3.2%) than C-TKA (1.6%) and N-TKA (1.5%) in initial analysis (p<0.001).
- Multivariate analysis revealed no significant difference in MUA rates between N-TKA, R-TKA, and C-TKA when controlling for confounding factors.
- Cementless/hybrid fixation and cruciate-retaining (CR) designs, more common in R-TKA, were independently associated with increased MUA risk.
Conclusions:
- Navigated and robotic-assisted TKA demonstrate comparable MUA rates to conventional TKA after adjusting for confounding variables.
- Robotic-assisted TKA utilization of cementless/hybrid fixation and CR implants increases the likelihood of MUA.
- These operative factors are crucial for risk-stratification and patient counseling regarding MUA likelihood after TKA.
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