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Validation of a Portable Tool for Conjunctival Ultraviolet Autofluorescence Imaging
Priya Bahra1, Lea Damnjanovic2,3, Koko Faen3
1School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, Australia.
Annals of Biomedical Engineering
|January 28, 2026
Summary
A new smartphone tool for conjunctival ultraviolet autofluorescence (CUVAF) imaging shows good agreement with traditional DSLR cameras. This affordable device can assess ocular sun exposure in clinical and field settings.
Area of Science:
- Ophthalmology
- Biomedical Imaging
- Public Health
Background:
- Conjunctival ultraviolet autofluorescence (CUVAF) is a key biomarker for ocular sun exposure and related conditions.
- Current CUVAF imaging relies on expensive and bulky DSLR camera systems, limiting accessibility.
Purpose of the Study:
- To evaluate a novel smartphone-based clip-on tool as a portable and cost-effective alternative for CUVAF imaging.
- To assess the validity of smartphone CUVAF imaging compared to a standard DSLR system.
Main Methods:
- 95 participants underwent CUVAF imaging using both DSLR and smartphone systems.
- Images were analyzed for CUVAF area ratio and intensity ratio.
- Bland-Altman analysis was used to compare agreement between the two imaging systems.
Main Results:
- Smartphone CUVAF imaging showed good agreement with the DSLR system.
- No significant difference was found in CUVAF intensity ratios between systems.
- Slight differences in CUVAF area ratios were observed, attributed to optical variations.
Conclusions:
- The smartphone-based CUVAF tool is a valid and promising alternative for assessing ocular UV exposure.
- This portable device facilitates broader clinical and field-based applications for eye health monitoring.
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