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Clinical application of capsule endoscopy in children with small bowel disease in Wuhan, China
Pingping Xu1, Dan Luo1, Baoxiang Wang1
1Department of Gastroenterology/Center of Digestive Endoscopy of Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technolog, Wuhan, China.
Insights
Capsule endoscopy (CE) is a safe and effective tool for diagnosing pediatric small intestinal diseases in Wuhan, demonstrating a high detection rate. Further promotion of CE is recommended for pediatric gastroenterology in the region.
Area of Science:
- Pediatric Gastroenterology
- Diagnostic Imaging
- Endoscopy
Background:
- Small intestinal diseases in children present diagnostic challenges.
- Capsule endoscopy (CE) offers a minimally invasive approach to visualize the small bowel.
- Evaluating the utility of CE in a specific pediatric population is crucial.
Purpose of the Study:
- To assess the clinical application value of capsule endoscopy (CE) for diagnosing small intestinal diseases in children in Wuhan.
- To determine the detection rate, completion rate, and safety of CE in this pediatric cohort.
Main Methods:
- Retrospective analysis of clinical data from children undergoing CE at Wuhan Children's Hospital (July 2021 - November 2024).
- Evaluation of CE completion rate, disease detection rate, small intestinal transit time, and adverse events.
- Analysis of indications for CE and specific diagnoses identified.
Main Results:
- 151 children (average age 10.9 years) underwent CE, with a 95.36% complete examination rate.
- Positive diagnostic findings in 76.82% of cases, including nonspecific small intestinal inflammation (46.6%) and Crohn's disease (19.9%).
- CE exhibited a high safety profile with no reported adverse reactions.
Conclusions:
- Capsule endoscopy demonstrates significant clinical value in diagnosing pediatric small intestinal diseases in Wuhan.
- The procedure is safe and effective, with a high disease detection rate.
- Wider adoption of CE is recommended for pediatric small bowel disease diagnosis.
Objective:
To evaluate the clinical application value of capsule endoscopy (CE) in the diagnosis of small intestinal diseases in children in Wuhan.
Methods:
A retrospective analysis was conducted on the clinical data of children who underwent CE examination at the Digestive Endoscopy Center of Wuhan Children's Hospital from July 2021 to November 2024. The completion rate of CE examination, disease detection rate, small intestinal transit time, and adverse reactions were analyzed.
Results:
Among the 151 children, 97 were male (64.24%) and 54 were female (35.76%), with an average age of 10.9 years. CE was swallowed orally in 133 cases (88.08%) and placed through gastroscopy in 18 cases (11.92%). Complete small intestinal examination was achieved in 144 cases (95.36%), with an average small intestinal transit time of 4 h and 11 min for those swallowed orally and 4 h and 16 min for those placed through gastroscopy. Seven cases (4.64%) did not complete the full small intestinal examination. Abdominal pain (99 cases, 65.56%), anemia (19 cases, 12.58%), and hematochezia and melena (23 cases, 15.23%) were the most common indications for examination. Among the 151 children, 116 (76.82%) had positive results, including 68 cases of nonspecific small intestinal inflammation, 29 cases of Crohn's disease, 4 cases of Henoch-Schönlein purpura, 6 cases of Meckel's diverticulum, 4 cases of small intestinal parasitic disease, 2 cases of collagenous gastritis, 1 case of melanocytic polyp, 1 case of lymphangiectasia, and 1 case of blue rubber bleb nevus syndrome. Nonspecific small intestinal inflammation was the most common in all age groups, while Crohn's disease was mainly seen in the 7-12 years and 13-18 years age groups, accounting for 55.17% and 44.83%, respectively. No adverse reactions occurred in all children.
Conclusion:
CE examination in children in Wuhan has a high disease detection rate and good safety. CE can be further promoted in the diagnosis of small intestinal diseases in children.
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