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Late Postoperative Persistent Hemorrhage Following Müller's Muscle-Conjunctival Resection: Management With Tranexamic
Yusuf Ziya Sahinoglu1, Mehmet Serhat Mangan2, Kardelen Aktan1
1Division of Ophthalmic Plastic and Reconstructive Surgery, Sadik Eratik Eye Institute, University of Health Sciences, Haydarpasa Numune Education and Research Hospital, Istanbul, Turkey.
The Journal of Craniofacial Surgery
|January 29, 2026
Summary
Post-Muller muscle-conjunctival resection, a patient experienced rare eyelid bleeding. Oral tranexamic acid effectively managed the hemorrhage, highlighting its potential role in managing post-operative bleeding complications.
Area of Science:
- Ophthalmology
- Surgical Complications
Background:
- Ptosis, or drooping of the upper eyelid, can be addressed surgically.
- Muller muscle-conjunctival resection is a surgical technique for ptosis correction.
- Postoperative bleeding is a potential, though uncommon, complication of ocular surgery.
Purpose of the Study:
- To report a case of postoperative hemorrhage following Muller muscle-conjunctival resection.
- To discuss the potential role of nutritional supplements in postoperative bleeding.
- To evaluate the efficacy of tranexamic acid in managing this type of hemorrhage.
Main Methods:
- A case study of a 38-year-old male patient with left upper eyelid ptosis.
- Phenylephrine testing confirmed suitability for Muller muscle-conjunctival resection.
- Management of postoperative bleeding with oral tranexamic acid after hematology consultation.
Main Results:
- The patient developed recurrent, spontaneous eyelid bleeding on postoperative days 4, 5, and 6.
- No history of bleeding disorders or anticoagulant medication use was reported.
- Oral tranexamic acid administration successfully resolved the bleeding episodes.
Conclusions:
- Hemorrhage is a rare but possible complication after Muller muscle-conjunctival resection.
- The influence of nutritional supplements on bleeding risk warrants consideration.
- Tranexamic acid provides a noninvasive and effective treatment option for managing post-Muller muscle resection bleeding.

