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High-Deductible Health Plans and Mortality Among Cancer Survivors
Justin M Barnes1,2, Arjun Gupta2,3, Meera Ragavan2,4
1Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.
JAMA Network Open
|January 29, 2026
Summary
High-deductible health plans (HDHPs) are linked to worse survival for cancer survivors, potentially due to financial barriers. HDHPs did not impact survival for those without a cancer history.
Area of Science:
- Health Economics
- Oncology
- Public Health
Background:
- High-deductible health plans (HDHPs) are increasingly common, offering lower premiums but higher out-of-pocket costs.
- Previous research indicates HDHPs are associated with reduced healthcare utilization among cancer survivors.
- The impact of HDHPs on cancer-specific outcomes remains unclear.
Purpose of the Study:
- To investigate the association between HDHP status and survival (overall and cancer-specific) in cancer survivors and individuals without a cancer history.
- To determine if financial barriers mediate the relationship between HDHP status and survival.
Main Methods:
- Cross-sectional study using data from the National Health Interview Survey (2011-2018).
- Included US adults aged 18-84.
- Analyzed overall survival (OS) and cancer-specific survival (CSS), adjusting for multiple covariates.
Main Results:
- HDHP status was associated with worse OS (HR, 1.46) and CSS (HR, 1.34) in cancer survivors.
- No significant association between HDHP status and mortality was found in adults without a cancer history (P for interaction = .001).
- Financial barriers mediated 30%-70% of the association between HDHP status and survival in cancer survivors.
Conclusions:
- HDHPs are linked to poorer survival outcomes for cancer survivors.
- The findings suggest that financial barriers associated with HDHPs may negatively impact necessary care and worsen cancer outcomes.
- HDHPs do not appear to affect mortality rates in the general adult population without a history of cancer.
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