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Guiding principles for implementing ESCMID clinical practice guidelines.

Bianca Albers1, Blin Nagavci2, Oana Joean3

  • 1Institute for Implementation Science in Health Care, University of Zurich, Zürich, Switzerland.

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
|January 29, 2026
PubMed
Summary
This summary is machine-generated.

Effective implementation of clinical practice guidelines (CPGs) requires understanding context, tailoring interventions, and monitoring progress. This guide offers best practices for quality CPG implementation to improve patient care.

Keywords:
Guideline implementationImplementation scienceInfection preventionRE-AIMReview

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Area of Science:

  • Healthcare Implementation Science
  • Evidence-Based Medicine
  • Quality Improvement in Healthcare

Background:

  • Clinical practice guidelines (CPGs) are crucial for standardizing medical practice and improving patient care.
  • Effective implementation is key to realizing the full benefits of CPGs.
  • This paper focuses on the ESCMID guidelines for infection prevention, diagnosis, and management.

Purpose of the Study:

  • To provide a guide to best practices for the quality implementation of clinical practice guidelines (CPGs).
  • To focus on the ESCMID guidelines for infection prevention, diagnosis, and management.
  • To leverage implementation science principles for effective CPG deployment.

Main Methods:

  • The guide is informed by implementation science.
  • It is based on the widely-used RE-AIM/PRISM implementation framework.
  • Key principles include understanding context, tailoring implementation, and monitoring progress.

Main Results:

  • A systematic approach to CPG implementation is essential.
  • Contextual understanding, tailored strategies, and monitoring are critical for success.
  • The RE-AIM/PRISM model provides a robust framework for planning and monitoring.

Conclusions:

  • Intentional, well-planned dissemination and implementation are vital for novel CPGs.
  • Rigorous evaluation of CPG outcomes ensures applicability, effectiveness, and sustainability.
  • Adopting a systematic, context-aware approach enhances CPG impact on patient care.