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Updated: Jan 31, 2026
08:04
Preparation of Functional Silica Using a Bioinspired Method
Published on: August 1, 2018
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Bioinspired material design for oral targeted delivery Systems: From structural bioinspiration to functional
Minhui Xu1, Tao Sun1, Huangbang Liang1
1College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha 410128, Hunan, China.
Biochemical Pharmacology
|January 29, 2026
Summary
Bioinspired materials (BMs) show great promise for oral targeted delivery systems (OTDS). This review analyzes BM design, function, and preparation methods to improve drug delivery efficiency for diseases like colitis and cancer.
Area of Science:
- Biomaterials Science
- Drug Delivery Systems
- Nanotechnology
Background:
- Bioinspired materials (BMs) are increasingly important for oral targeted delivery systems (OTDS).
- Current research often focuses on specific diseases or material types, lacking a systematic overview.
- Understanding preparation methods' impact on delivery performance is limited.
Purpose of the Study:
- To comprehensively analyze BM design strategies and functional mechanisms for OTDS.
- To critically evaluate preparation methods for BMs in drug delivery.
- To provide a systematic review of BMs for improving oral drug targeting efficiency.
Main Methods:
- Analysis of structural and biological emulation strategies in BMs.
- Evaluation of advantages and limitations of various BM preparation methods.
- Synthesis of experimental evidence from diverse disease models, including colitis and cancer.
Main Results:
- BMs enhance oral drug delivery efficiency by mimicking biological systems.
- Structural and biological emulation are key dimensions for BM design in OTDS.
- Preparation methods significantly influence the performance of BMs in drug delivery.
Conclusions:
- BMs offer a novel paradigm for rational design of effective OTDS.
- Further research is needed to optimize BM preparation and delivery strategies.
- This review facilitates the rational design and clinical application of next-generation OTDS.
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