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Complex mast cell CCL2-chemokine trafficking patterns during local allergic responses.

Juan Eduardo Montero-Hernández1, Shamila Vibhushan1, Manuela Bratti2

  • 1Centre de Recherche sur l'Inflammation, Université Paris Cité, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1149, Centre National de la Recherche Scientifique (CNRS) EMR8252, Faculté de Médecine Site Bichat, Paris, France; Laboratoire d'Excellence Inflamex, Université Paris Cité, Paris, France.

The Journal of Allergy and Clinical Immunology
|January 29, 2026
PubMed
Summary

Mast cells (MC) release C-C Motif Chemokine Ligand 2 (CCL2) through complex vesicular trafficking, influencing local inflammation during allergic responses. This study details CCL2

Keywords:
CCL2chemokinemast cellspassive cutaneous anaphylaxissecretiontrafficking

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