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Updated: Jan 31, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Bridging the knowledge gap: Med Wise Rx helps older adults navigate comprehensive medication reviews
The Med Wise Rx™ program significantly improved older adults' understanding of Comprehensive Medication Reviews (CMR) and their benefits. This knowledge was sustained six months post-training, addressing underutilization of this vital pharmacy service.
Area of Science:
- Geriatric Pharmacy
- Medication Safety
- Health Literacy
Background:
- Older adults face high risks of medication-related problems.
- Comprehensive Medication Reviews (CMR) are underutilized despite Medicare reimbursement.
- The Med Wise Rx™ program aims to boost older adults' engagement with CMR services.
Purpose of the Study:
- To evaluate the Med Wise Rx™ training's effectiveness in enhancing older adults' comprehension of CMRs.
- To assess participants' understanding of CMR benefits and their self-efficacy in seeking these services.
Main Methods:
- A waitlist control trial involved virtual sessions on medication safety and communication skills.
- Participants engaged with tools including practice questions and communication strategy modeling.
- Understanding of CMRs was assessed via open-ended survey questions at baseline, 8 weeks, and 6 months, analyzed using deductive content analysis.
Main Results:
- Baseline understanding of CMRs was low (21%).
- Post-training, 86% understood CMR components at 8 weeks, rising to 93% at 6 months.
- Knowledge about CMR processes and benefits was retained at the 6-month follow-up.
Conclusions:
- Med Wise Rx™ effectively enhanced older adults' ability to articulate what a CMR is and its advantages.
- Further research will explore the link between improved understanding and actual CMR service utilization.
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