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Multi-Institutional Drug Use Patterns in Hospitalized Older Patients: Retrospective Cross-Sectional Study.

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Summary
This summary is machine-generated.

This study redefines polypharmacy for older inpatients, proposing 10-19 drugs as a more appropriate threshold than the traditional 5. This updated definition better reflects the complex medication needs of this population.

Keywords:
Common Data Modelelectronic health recordmedicationolder patientspolypharmacy

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Area of Science:

  • Geriatric Medicine
  • Clinical Pharmacy
  • Health Services Research

Background:

  • Aging populations increase chronic diseases and polypharmacy.
  • Limited research exists on polypharmacy criteria for older inpatients across multiple institutions.

Purpose of the Study:

  • To analyze polypharmacy patterns in geriatric inpatients.
  • To establish appropriate criteria for defining polypharmacy in this demographic.

Main Methods:

  • Analysis of electronic health records from 4 medical institutions (2012-2020).
  • Inclusion of patients aged 65 years and older.
  • Literature review and international guidelines informed polypharmacy level determination.

Main Results:

  • A 4-level polypharmacy system (nonpolypharmacy, polypharmacy, major polypharmacy, excessive polypharmacy) was proposed.
  • Major polypharmacy (10-19 drugs) is suggested as a more fitting threshold than the traditional 5+ drugs for hospitalized older adults.
  • Commonly prescribed drugs in the major polypharmacy group included antibacterials, anesthetics, and cardiac therapies.

Conclusions:

  • A novel polypharmacy categorization system for older inpatients is presented.
  • The proposed system challenges the conventional definition of 5 or more concomitant drugs.
  • The higher disease and drug burden in older inpatients, including those undergoing major surgery, supports the adjusted threshold.