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Updated: Jan 31, 2026
09:41
An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
Published on: July 15, 2015
9.1K
Bispecific Antibody Therapy for Multiple Myeloma: A Practical Toolkit
Cesar Rodriguez1, Cyrille Touzeau2, Edvan de Queiroz Crusoe3
1The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
Clinical Lymphoma, Myeloma & Leukemia
|January 29, 2026
Summary
Bispecific antibodies offer a new treatment for relapsed/refractory multiple myeloma. This guidance details best practices for patient management and delivery to improve outcomes with these novel therapies.
Area of Science:
- Hematology
- Oncology
- Immunotherapy
Background:
- Bispecific antibodies represent a novel therapeutic class for relapsed/refractory multiple myeloma.
- Effective patient management and delivery are crucial for optimizing outcomes with these agents.
Purpose of the Study:
- To provide expert consensus on best practices for bispecific antibody therapy in multiple myeloma.
- To educate healthcare professionals on the practical aspects of implementing bispecific antibody treatment.
Main Methods:
- A panel of 5 experienced hematologists convened to discuss bispecific antibody therapy.
- Consensus was reached on key considerations and best practice recommendations.
Main Results:
- The paper outlines best practices for the entire patient journey.
- Key stages include patient eligibility, pretreatment, step-up dosing, treatment administration, adverse event management, and long-term care.
Conclusions:
- Expert insights aim to guide the real-world implementation of bispecific antibody therapy.
- This guidance is expected to enhance healthcare professional education and optimize patient outcomes.
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