Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

66.0K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
66.0K
Brain Waves01:23

Brain Waves

4.1K
Brain waves are electrical signals generated by the neurons in the brain, which are regularly monitored to measure mental activities. Brain waves and their frequency ranges can be measured using an electroencephalogram or EEG. There are four main types of brain waves, each with distinct characteristics:
4.1K
Organization of the Brain01:30

Organization of the Brain

2.7K
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
2.7K
Brain Imaging01:14

Brain Imaging

734
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
734
Perpendicular-Axis Theorem01:16

Perpendicular-Axis Theorem

4.6K
The perpendicular-axis theorem states that the moment of inertia of a planar object about an axis perpendicular to its plane is equal to the sum of the moments of inertia about two mutually perpendicular concurrent axes lying in the plane of the body.
Consider a circular disc of mass M and radius R lying along an x-y plane. The origin lies at the center of the disc, and the z-axis is perpendicular to the disc's plane. All three axes coincide at the disc's center. The moment of inertia of this...
4.6K
Parallel-axis Theorem01:06

Parallel-axis Theorem

8.3K
The parallel-axis theorem provides a convenient and quick method of finding the moment of inertia of an object about an axis parallel to the axis passing through its center of mass. Consider a thin rod as an example. There is a striking similarity between the process of finding the moment of inertia of a thin rod about an axis through its middle, where the center of mass lies, and about an axis through its end using the conventional method. In the conventional method, the concept of linear mass...
8.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Elevated CSF Beta Trace Protein Levels in Patients with CSF-Venous Fistulas.

AJNR. American journal of neuroradiology·2026
Same author

Clinical Presentation, Misdiagnosis, and Imaging Findings of Anterior Disc Herniations.

AJNR. American journal of neuroradiology·2026
Same author

Blood-Pressure Control after Intracerebral Hemorrhage - An Unbroken Glass Ceiling.

The New England journal of medicine·2026
Same author

Art of imaging: brain sagging in spinal cerebrospinal fluid leak.

Radiology advances·2026
Same author

Occurrence of CSF-Venous Fistulas by Spinal Level and Laterality.

AJNR. American journal of neuroradiology·2026
Same author

Chiari Decompression in Patients with Spontaneous Intracranial Hypotension: Presenting Symptoms and Treatment Response.

AJNR. American journal of neuroradiology·2026

Related Experiment Video

Updated: Jan 31, 2026

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
04:20

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure

Published on: October 1, 2019

6.3K

Heart-Brain Axis: Subclinical Cardiovascular Changes and Brain Health.

Parnian Habibi1, Lin Yee Chen2, Farzaneh A Sorond3

  • 1Department of Radiology Mayo Clinic Rochester MN USA.

Journal of the American Heart Association
|January 30, 2026
PubMed
Summary
This summary is machine-generated.

Subclinical heart-brain axis dysfunction, even without disease, impacts brain health and cognitive function. Early detection and intervention are crucial for preserving brain health and preventing neurological decline.

Keywords:
brain healthheart–brain Axissubclinical

More Related Videos

Rodent Heart and Brain Tissue Preparation for Digital Macro Photography after Ischemia-reperfusion
06:27

Rodent Heart and Brain Tissue Preparation for Digital Macro Photography after Ischemia-reperfusion

Published on: February 1, 2022

4.5K
Dissection Techniques and Histological Sampling of the Heart in Large Animal Models for Cardiovascular Diseases
10:53

Dissection Techniques and Histological Sampling of the Heart in Large Animal Models for Cardiovascular Diseases

Published on: June 16, 2022

9.6K

Related Experiment Videos

Last Updated: Jan 31, 2026

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
04:20

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure

Published on: October 1, 2019

6.3K
Rodent Heart and Brain Tissue Preparation for Digital Macro Photography after Ischemia-reperfusion
06:27

Rodent Heart and Brain Tissue Preparation for Digital Macro Photography after Ischemia-reperfusion

Published on: February 1, 2022

4.5K
Dissection Techniques and Histological Sampling of the Heart in Large Animal Models for Cardiovascular Diseases
10:53

Dissection Techniques and Histological Sampling of the Heart in Large Animal Models for Cardiovascular Diseases

Published on: June 16, 2022

9.6K

Area of Science:

  • Neuroscience
  • Cardiovascular Science
  • Gerontology

Background:

  • The heart-brain axis integrates neural regulation of cardiovascular function and cardiovascular impacts on brain health.
  • Subclinical cardiovascular changes can lead to brain injury and cognitive vulnerability, even without diagnosed disease.

Purpose of the Study:

  • To review how subclinical heart-brain axis dysfunction affects brain structure and function.
  • To highlight biomarkers for silent brain injury and cognitive decline.
  • To outline mechanisms and future research directions for early detection and prevention.

Main Methods:

  • Literature review synthesizing current knowledge on the heart-brain axis.
  • Discussion of neural pathways, hormonal signaling, and biomarkers.
  • Identification of mechanistic pathways and research gaps.

Main Results:

  • Subclinical heart-brain axis dysfunction contributes to neurological decline.
  • Biomarkers for silent brain injury, cognitive decline, and dementia are identified.
  • Mechanistic pathways link cardiovascular changes to adverse brain outcomes.

Conclusions:

  • Subclinical heart-brain axis dysfunction is a significant factor in brain health.
  • Early risk stratification using biomarkers is essential.
  • Future research should focus on early detection and preventive strategies to preserve brain health.