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Updated: Jan 31, 2026
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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
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Biological sex-dependent differences in acute and post-acute stroke care-a population-based case-control study
Lukas Mayer-Suess1, Kurt Moelgg1, Heinrich Rinner2
1Department of Neurology, Medical University Innsbruck, Innsbruck, Austria.
European Stroke Journal
|January 30, 2026
Summary
Sex disparities in stroke care are minimal within a structured pathway. However, differences in diagnostics, mortality, and readmissions between men and women warrant further investigation for improved stroke treatment.
Area of Science:
- Neurology
- Public Health
- Health Services Research
Background:
- Previous studies on sex disparities in stroke care relied on limited observational data.
- A comprehensive analysis of the entire stroke treatment pathway is needed to understand sex-based differences.
Purpose of the Study:
- To conduct a comprehensive analysis of sex-based disparities across the entire stroke care pathway.
- To evaluate differences in stroke incidence, in-hospital care, and post-stroke outcomes between men and women.
Main Methods:
- Utilized the quality-controlled, population-based Tyrolean Stroke Care pathway (2019-2023).
- Analyzed data from all ischemic stroke cases, covering the entire patient journey from initial call to recurrent stroke re-hospitalization.
- Adjusted for age, National Institute of Stroke Scale (NIHSS), and pre-stroke modified Rankin Scale (mRS).
Main Results:
- 5733 ischemic stroke cases analyzed; men had a higher incidence of first stroke.
- After adjustments, no significant differences in pre-hospital care or rehabilitation access were observed.
- Women were less likely to be admitted to stroke units and undergo MRI/echocardiography but had fewer in-house complications.
- Men showed higher all-cause mortality and recurrent stroke-related re-admission rates.
Conclusions:
- Highly structured stroke care pathways minimize sex disparities in overall care.
- Specific differences in diagnostic utilization, post-stroke mortality, and recurrent stroke rates between sexes require further research.
- These findings highlight areas for targeted interventions to improve stroke care equity.
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