Acceptability and Feasibility of Internet-Based Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder in
Maria Alice de Mathis1, Oskar Flygare2, Daniel L C Costa1
1Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo; Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders.
Behavior Therapy
|January 31, 2026
Summary
Internet-based cognitive-behavior therapy (ICBT) effectively treated Obsessive-Compulsive Disorder (OCD) in Brazil. The program showed significant symptom reduction and remission rates, indicating feasibility for wider implementation.
Area of Science:
- Mental Health
- Psychiatry
- Digital Health
Background:
- Obsessive-Compulsive Disorder (OCD) presents a significant global mental health challenge.
- Access to evidence-based treatments like cognitive-behavioral therapy (CBT) can be limited in certain regions.
- Internet-based CBT (ICBT) offers a scalable solution to bridge treatment gaps.
Purpose of the Study:
- To evaluate the implementation and effectiveness of a Swedish-developed ICBT program for OCD in Sao Paulo, Brazil.
- To adapt and translate the OCD-NET treatment manual for a Brazilian context.
- To assess treatment outcomes using the RE-AIM framework.
Main Methods:
- An open-label trial involving 35 adults diagnosed with OCD.
- Delivery of a 10-module ICBT program based on Exposure and Response Prevention (EPR).
- Evaluation using the RE-AIM framework and the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) for OCD severity and PHQ-9 for depressive symptoms.
Main Results:
- High completion rate (85.7%) with 30 out of 35 participants finishing the ICBT protocol.
- Significant reduction in OCD severity, with 60% achieving treatment response and 30% remission at 6-month follow-up.
- Improvements observed in depressive symptoms (PHQ-9 scores).
Conclusions:
- ICBT is a feasible and effective treatment for OCD in an upper-middle-income country context.
- The adapted OCD-NET program shows promise for wider implementation.
- Further research is needed to explore ICBT's acceptability in underserved populations.
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