Framework Doping Enhances COF-DNA Nanoplatforms for Dual RNA Imaging and Phototherapy

Peng Gao1, Mengyao Yu1, Ruyue Wei1

  • 1College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institute of Molecular and Nano Science, Shandong Normal University, Jinan 250014, P. R. China.

Analytical Chemistry
|February 1, 2026
PubMed
Summary

This study introduces a new method for engineering DNA-based covalent organic frameworks (COFs) for cancer theranostics. The strategy optimizes both imaging and therapy, enabling precise cancer cell detection and destruction.

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