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Re-evaluating the prospective prediction of near-term suicide attempt using a Go/No-go task
Petty Tineo1, Vibha Reddy2, Chintan V Dave3
1War Related Illness and Injury Study Center (WRIISC), VA New Jersey Health Care System, East Orange, NJ, United States.
Journal of Affective Disorders
|February 1, 2026
Summary
Motor impulsivity influences suicidal behavior. A Go/No-go task revealed reduced false alarms and increased drift efficiency predict actual suicide attempts (ASA), not other events.
Area of Science:
- Neuroscience
- Psychology
- Computational Psychiatry
Background:
- Motor impulsivity is a key factor in the progression from suicidal thoughts to actions.
- Previous research linked increased motor impulsivity and decreased decisional efficiency to suicide attempts.
Purpose of the Study:
- To investigate a simplified Go/No-go (GNG) task in Veterans with a history of suicidal behavior.
- To identify neurocognitive markers associated with actual suicide attempts (ASA) versus other suicide-related events (OtherSE).
Main Methods:
- Veterans completed multiple GNG sessions over one year.
- Sessions were categorized based on subsequent ASA, OtherSE, or no suicide-related events (noSE) within 90 days.
- Computational modeling analyzed cognitive variables from the GNG task.
Main Results:
- Reduced false alarms in behavioral data were associated with upcoming ASA compared to noSE.
- Increased drift efficiency for 'foil' stimuli in computational modeling predicted upcoming ASA.
- These specific cognitive markers were not linked to upcoming OtherSE.
Conclusions:
- Neurocognitive markers from the GNG task, specifically reduced false alarms and increased drift efficiency, may serve as indicators of short-term risk for actual suicide attempts.
- Distinct cognitive processes differentiate actual suicide attempts from other suicide-related events.
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