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Updated: Feb 4, 2026

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Fragility Assessment of Bovine Cortical Bone Using Scratch Tests
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An Extremely Low-Birth-Weight Infant With Bone Fragility Due to Fanconi Syndrome
Rei Yoshida1, Miku Hosokawa1, Toshiko Ukawa1
1Department of Neonatology, Japanese Red Cross Medical Center, Hiroo, Shibuya-ku, Tokyo, Japan.
Kidney Medicine
|February 2, 2026
Summary
Fanconi syndrome, a rare kidney disorder, affected an extremely low-birth-weight infant, causing severe rickets and bone fragility. Treatment was challenging, but renal function improved by six months.
Area of Science:
- Pediatric Nephrology
- Neonatal Medicine
- Clinical Case Study
Background:
- Fanconi syndrome is a renal proximal tubule dysfunction causing rickets and growth failure in children.
- Reports in neonates, particularly extremely low-birth-weight (ELBW) infants, are rare.
- This case highlights the challenges of diagnosing and managing Fanconi syndrome in ELBW neonates.
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