Related Experiment Video
Updated: Feb 4, 2026

Who is Who? Non-invasive Methods to Individually Sex and Mark Altricial Chicks
Published on: May 24, 2014
Correlation Between Vitamin D and TSH Levels in Healthy Controls and Individuals with Hypothyroidism According to Age
Sara Abaza1, Diya Hasan1, Mutaz Jamal Al-Khreisat2
1Department of Allied Medical Sciences, Zarqa College, Al-Balqa Applied University, Zarqa, Jordan.
Background:
Elevated levels of circulating 25-hydroxyvitamin D (25 (OH) D) are correlated with reduced levels of circulating thyroid-stimulating hormone (TSH).
Objective:
The aim of this study was to evaluate the relationship between vitamin D and circulating TSH levels based on sex and age, with a focus on thyroid autoimmunity and thyroid hormone levels.
Methods:
Fifty samples were obtained from patients with hypothyroidism (Hashimoto's thyroiditis, HT) aged 18-59 years (49.4% men, 50.6% women). The samples were tested for serum vitamin D and TSH levels using the enzyme-linked immunosorbent assay.
Results:
The mean TSH level in the HT group (5.97 ± 0.18) was significantly higher than that in the control group (1.61 ± 0.1) (P < 0.001). Conversely, the mean vitamin D level was significantly lower in the HT group (40.5 ± 0.72) than in the control group (57.3 ± 0.72) (P < 0.001). Differences based on sex were not statistically significant (P = 0.096). Similarly, no differences were observed in age group distributions. Overall, moderate and strong positive correlations were observed in the control (r = 0.4767, P = 0.0009) and HT (r = 0.7493, P < 0.0001) groups, respectively.
Conclusion:
This study showed a negative correlation between serum vitamin D and TSH levels in both healthy controls and patients with HT, regardless of age and sex.
More Related Videos
07:22Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
Published on: March 7, 2025
08:18Author Spotlight: Unraveling Vitamin A Transport Mechanisms — Linking Liver Receptors to Vision Health Through RBPR2 and RBP4 Interactions
Published on: October 4, 2024
Related Concept Videos
Correlations
Correlation and Causation
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
Vitamins
Sex-linked Disorders
Correlation
Two variables, for example, a and b, are said to be positively correlated if both variables move in the same direction. In other words, a positive correlation exists between two variables, a and b, if:
Impact of Individuals on Individuals