Related Experiment Video
Updated: Feb 4, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
Anlotinib plus Chemotherapy for the Treatment of Refractory Primary Cardiac Intimal Sarcoma: A Case Report
Wenqiang Guan1, Hongyu Guan2, Jidong Miao1
1Department of Oncology, Zigong Fourth People's Hospital, Zigong, China.
Introduction:
Primary cardiac intimal sarcoma (CIS) is a rare and highly malignant soft tissue tumor associated with an extremely poor prognosis. To date, there are no established treatment guidelines for CIS in clinical practice.
Case Presentation:
A 44-year-old man was diagnosed with left atrial intimal sarcoma. Forty-two days after radical surgical resection, he developed local recurrence accompanied by brain and gluteus medius metastases. The patient first received emergency radiotherapy for intracranial metastases, followed by six cycles of systemic chemotherapy with ifosfamide and epirubicin, combined with targeted therapy using anlotinib. Ultimately, he achieved an overall survival (OS) of 17 months.
Conclusion:
To our knowledge, this is the first report describing the therapeutic efficacy of anlotinib in CIS. This case highlights the potential role of anlotinib as a promising therapeutic option for this rare and aggressive malignancy.
Related Concept Videos
Data Reporting and Recording
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Two synthetic agonists of THC,...
Types of Reports I: Hands-off Report
Following are the key components and categories of hand-off reports:
Purpose and Process:
Types of Reports II: Incident or Occurrence Report
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Types of Reports III: Telephone and Verbal Reports
Here's an overview of each type:
Telephone Orders

