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Published on: October 16, 2016
Remote monitoring tools in rheumatoid arthritis patients: FACIT-fatigue and HAQ
Elena Grau García1, Pablo Francisco Muñoz Rodriguez2, Hikmat Charia1
1Rheumatology Research Group, Instituto de Investigaciones Sanitarias La Fe, Valencia, Spain.
Objective:
To analyze the association of clinical activity with pain, fatigue and disability in patients with RA.
Methods:
Prospective observational study of 3 months of follow-up in 60 patients who initiate biological or anti-JAK therapy. We analyzed changes in the PROs reported by patients through FACIT-fatigue, HAQ questionnaires and pain VAS. Clinical activity through DAS28, DAS28-CRP, SDAI and CDAI index was measured.
Results:
We observed a statistically significant association between clinical activity and the fatigue, pain and disability (p<0.001). A greater fatigue was associated with a greater perception of pain and high tender joint number (p=0.002). Patients who discontinued treatment presented higher fatigue (p=0.044) and disability (p=0.0013) than those who continued treatment, regardless of the type of treatment, the time of evolution, as well as whether or not they had received previous biological therapies.
Conclusion:
PROs would be helpful in the disease control in cases where a remote monitoring is needed, since PROs showed a significant association with clinical activity in RA.
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