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Related Concept Videos

Plant Hormones01:56

Plant Hormones

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Plant hormones—or phytohormones—are chemical molecules that modulate one or more physiological processes of a plant. In animals, hormones are often produced in specific glands and circulated via the circulatory system. However, plants lack hormone-producing glands.
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Types of Hormones02:13

Types of Hormones

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Hormones can be classified into three main types based on their chemical structures: steroids, peptides, and amines. Their actions are mediated by the specific receptors they bind to on target cells.
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Types of Hormones01:21

Types of Hormones

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Hormones are classified into four main groups: steroids, eicosanoids, amino acid-based derivatives, and peptide hormones.
Steroids and eicosanoids fall under the category of lipid-soluble hormones. Steroids are derived from cholesterol and feature four interconnected carbon rings with variable side chains. Notable examples include estradiol from ovaries and testosterone from testes, exemplifying the critical roles of these lipid-soluble hormones in reproductive physiology. Eicosanoids, derived...
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Hormonal Regulation01:33

Hormonal Regulation

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The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
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Hormonal Regulation01:40

Hormonal Regulation

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Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
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Primary and Secondary Growth in Roots and Shoots03:02

Primary and Secondary Growth in Roots and Shoots

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Vascular plants, which account for over 90% of the Earth’s vegetation, all undergo primary growth—which lengthens roots and shoots. Many land plants, notably woody plants, also undergo secondary growth—which thickens roots and shoots.
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Articles linked to this work by shared authors, journal, and citation graph.

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Cumulative effects of lifelong systemic excess growth hormone on postcranial skeletal morphology in adult mice.

Journal of anatomy·2026
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GH-resistant (Laron) mice: gene therapy with a liver-specific GH receptor causes unbalanced upregulation of female-biased and growth-related genes.

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Reproductive experience promotes permanent body growth independently of growth hormone.

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Growth hormone receptor antagonism improves tumoral chemo-immunotherapy response in a mouse model of lung cancer.

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Standardized Perioperative Protocols Are Associated With Reduced Length of Stay and Readmission in Cushing Disease: Results From the Multicenter RAPID Study.

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Related Experiment Video

Updated: Feb 4, 2026

A Modified In vitro Invasion Assay to Determine the Potential Role of Hormones, Cytokines and/or Growth Factors in Mediating Cancer Cell Invasion
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A Modified In vitro Invasion Assay to Determine the Potential Role of Hormones, Cytokines and/or Growth Factors in Mediating Cancer Cell Invasion

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Growth Hormone, Not Simply Just a Hormone for Growth.

Kevin C J Yuen1,2,3, Jaime Guevara-Aguirre4,5,6, John J Kopchick7,8,9

  • 1Division of Neuroendocrinology, Department of Neurology, Barrow Neurological Institute, Phoenix, AZ, USA. kevin.yuen@commonspirit.org.

Endocrinology and Metabolism (Seoul, Korea)
|February 2, 2026
PubMed
Summary

Growth hormone (GH) influences glucose metabolism, fibrosis, and cancer. This review explores GH

Keywords:
FibrosisGlucoseGrowth hormoneInsulin-like growth factor INeoplasms

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Comparative Analysis of Human Growth Hormone in Serum Using SPRi, Nano-SPRi and ELISA Assays
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Comparative Analysis of Human Growth Hormone in Serum Using SPRi, Nano-SPRi and ELISA Assays
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Area of Science:

  • Endocrinology
  • Molecular Biology
  • Metabolic Research

Background:

  • Growth hormone (GH) has diverse physiological effects beyond growth promotion.
  • Recombinant human GH is used therapeutically for growth deficiency and metabolic health.
  • Dysregulated GH levels reveal less understood GH actions.

Purpose of the Study:

  • To review the non-classic roles of GH and IGF-I.
  • To focus on GH's interplay with glucose metabolism, fibrosis, and carcinogenesis.
  • To integrate findings from cellular, animal, and human studies.

Main Methods:

  • Literature review focusing on GH's effects beyond classic applications.
  • Analysis of clinical data from acromegaly and GH deficiency patients.
  • Integration of molecular, cellular, animal, and human study findings.

Main Results:

  • GH dysregulation is linked to altered glucose metabolism, fibrosis, and carcinogenesis.
  • GH and Insulin-like Growth Factor I (IGF-I) exert subtle, less evident actions.
  • Novel molecular pathways underlying these subtle actions are being elucidated.

Conclusions:

  • GH's role extends to complex metabolic and disease processes.
  • Understanding GH's subtle actions is crucial for novel therapeutic strategies.
  • Further research into GH and IGF-I molecular pathways is warranted.