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Clinical performance of BioCoat™ and Fissurit FX: a randomized 18-month split-mouth study
Esra Ergün1, Canan Bayraktar Nahir2
1Department of Pediatric Dentistry, Faculty of Dentistry, Tokat Gaziosmanpaşa University, Tokat, Türkiye.
Odontology
|February 2, 2026
Summary
This study compared bioactive pit and fissure sealants (BioCoat™) with conventional sealants (Fissurit FX) in children over 18 months. Both sealant types demonstrated similar effectiveness in preventing caries, with no significant differences in retention or secondary caries.
Area of Science:
- Pediatric Dentistry
- Dental Materials Science
- Preventive Dentistry
Background:
- Pit and fissure sealants (PFS) are crucial for preventing occlusal caries.
- Evaluating novel bioactive sealants against conventional options is essential for optimizing caries prevention strategies.
Purpose of the Study:
- To compare the 18-month clinical performance of a bioactive resin-based sealant (BioCoat™) versus a conventional resin-based sealant (Fissurit FX).
- To assess the influence of patient-related factors on sealant success.
Main Methods:
- A randomized split-mouth clinical study involving 63 pediatric patients (aged 7-9).
- BioCoat™ and Fissurit FX were applied to contralateral mandibular first molars.
- Clinical evaluations used modified USPHS criteria, with Kaplan-Meier survival analysis and logistic regression applied.
Main Results:
- At 18 months, success rates were 90.2% for BioCoat™ and 88.2% for Fissurit FX, with no statistically significant difference.
- Both materials exhibited comparable performance in marginal adaptation, retention, and secondary caries prevention.
- No significant effect of patient-related factors on material success was observed.
Conclusions:
- BioCoat™ demonstrates comparable long-term clinical performance to Fissurit FX.
- The bioactive properties of BioCoat™ may offer additional preventive benefits, supporting its use in pediatric dentistry.
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