Related Experiment Video
Updated: Feb 4, 2026

Assessing Specificity of Anticancer Drugs In Vitro
Published on: March 23, 2016
QSPR analysis of anticancer drugs using the Euler-Sombor index and theoretical insights on its minimum value for
Swathi Shetty1, B R Rakshith2, N V Sayinath Udupa1
1Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, India.
Abstract:
Topological indices (TIs) are powerful tools for exploring the relationship between molecular structure and drug activity, offering a cost-effective alternative to experimental screening. The Euler-Sombor index, a recently introduced degree-based TI, captures key structural features of molecules that influence their physico-chemical behaviour. This study investigates the use of the Euler-Sombor index in quantitative structure-property relationship (QSPR) modeling of anticancer drugs. By applying linear, quadratic, and logarithmic regression models, we predict important properties such as boiling point (BP), melting point (MP), enthalpy (E), and molar refraction (MR). The results show a significant correlation between the Euler-Sombor index and these molecular properties. In addition, we extend the result of Su and Tang by characterizing unicyclic graphs that have the third minimum Euler-Sombor index.
Related Concept Videos
Euler Equations of Motion
Euler's Equations of Motion
Euler's Formula to Columns with Other End Conditions
Euler's Formula to Columns: Problem Solving
The system comprises two vertical rigid bars, AB and BC, of...
Ogive Graph
Graphing Antiderivatives

