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Sexual dysfunction in women with migraines: a systematic review
Karina Stech1, Anupama Jayachandran2, Huaqing Zhao3
1Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA. karina.stech@gmail.com.
Archives of Women'S Mental Health
|February 3, 2026
Summary
Sexual dysfunction affects a high percentage of women with migraines, with a pooled prevalence of 69%. Migraine characteristics and psychological factors like anxiety and depression contribute to this common comorbidity.
Area of Science:
- Neurology
- Reproductive Health
- Psychiatry
Background:
- Migraine significantly impacts women's quality of life.
- Sexual dysfunction is a prevalent issue, but its association with migraine requires further investigation.
Purpose of the Study:
- To determine the prevalence of sexual dysfunction in women with migraines.
- To explore factors linking sexual dysfunction and migraine in women.
Main Methods:
- Systematic review of studies from PubMed, MEDLINE, and CINAHL databases.
- Inclusion of 16 studies with 1,715 participants.
- Data extraction and assessment by two independent reviewers.
Main Results:
- Pooled prevalence of sexual dysfunction in women with migraine was 69% (95% CI 61-77%).
- Prevalence rates ranged from 22.6% to 90%, with significant heterogeneity.
- Migraine characteristics (duration, frequency, pain) and psychological factors (anxiety, depression) were associated with sexual dysfunction.
Conclusions:
- Sexual dysfunction is common in women with migraines.
- Clinicians should screen migraine patients for sexual dysfunction.
- Anxiety and depression may play a crucial role in this association.
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