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Updated: Feb 5, 2026
08:35
Elastomeric PGS Scaffolds in Arterial Tissue Engineering
Published on: April 8, 2011
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Bioresorbable Scaffolds: Ready for a Rematch?
Oludamilola Akinmolayemi1,2, Alexander Levy1,2, Swagata Patnaik3
1Icahn School of Medicine at Mount Sinai, The Zena and Michael A. Weiner Cardiovascular Institute, New York, NY, USA.
Current Cardiology Reports
|February 3, 2026
Summary
Bioresorbable vascular scaffolds (BVS) show higher early event rates compared to drug-eluting stents (DES). While long-term outcomes improve, BVS technology requires further development and testing before widespread clinical use.
Area of Science:
- Cardiovascular research
- Medical device technology
Background:
- Bioresorbable vascular scaffolds (BVS) offer theoretical advantages over traditional metallic drug-eluting stents (DES).
- Early randomized controlled trials (RCTs) revealed challenges in clinical application for first-generation BVS.
Purpose of the Study:
- To review outcomes of early-generation BVS.
- To provide updates on advancements in newer scaffold technologies and delivery methods.
Main Methods:
- Analysis of pooled individual patient data from ABSORB studies with 5-year follow-up.
- Review of outcomes comparing BVS with metallic DES.
Main Results:
- Pooled data showed higher event rates in the BVS group within the first three years.
- After three years, BVS event rates were comparable or lower than metallic DES.
- Current BVS technology is not yet ready for widespread clinical adoption.
Conclusions:
- Further improvements in BVS technology are necessary.
- New BVS generations require rigorous testing against metallic DES in large-scale RCTs with long-term follow-up.
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