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Updated: Feb 5, 2026

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats
Published on: May 27, 2021
Inhibitory control and voluntary tic suppression
1Department of Psychology, McGill University, Montréal, QC, Canada; Department of Psychology, Université du Québec à Montréal, Montréal, QC, Canada.
Individuals with Tourette syndrome (TS) can voluntarily suppress tics, a unique ability differentiating it from other movement disorders. Research on inhibitory control in TS shows mixed results, and the mechanisms of tic suppression require further understanding.
Area of Science:
- Neuroscience
- Movement Disorders
- Psychiatry
Background:
- Tics are involuntary movements/vocalizations characteristic of Tourette syndrome (TS).
- Voluntary tic suppression is a key feature of TS, allowing brief control over tics.
- Existing research on inhibitory control and response inhibition in TS has yielded inconsistent findings.
Purpose of the Study:
- To review evidence on inhibitory control of voluntary actions in TS.
- To explore the mechanisms underlying voluntary tic suppression in Tourette syndrome.
- To compare inhibitory control and tic suppression processes in TS.
Main Methods:
- Review of clinical studies.
- Analysis of behavioral and neuropsychological data.
- Examination of neurobiologic evidence.
Main Results:
- Inhibitory control studies in TS have produced mixed results.
- Mechanisms of voluntary tic suppression in Tourette syndrome are not well understood.
- The relationship between inhibitory control and voluntary tic suppression requires further investigation.
Conclusions:
- Further research is needed to clarify the mechanisms of voluntary tic suppression in TS.
- Understanding inhibitory control may offer insights into tic expression and suppression.
- Distinguishing TS from other movement disorders relies on understanding these unique control capacities.
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